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The structure, function and properties of sirohaem decarboxylase - an enzyme with structural homology to a transcription factor family that is part of the alternative haem biosynthesis pathway

Some bacteria and archaea synthesize haem by an alternative pathway, which involves the sequestration of sirohaem as a metabolic intermediate rather than as a prosthetic group. Along this pathway the two acetic acid side-chains attached to C12 and C18 are decarboxylated by sirohaem decarboxylase, a...

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Detalles Bibliográficos
Autores principales: Palmer, David J, Schroeder, Susanne, Lawrence, Andrew D, Deery, Evelyne, Lobo, Susana A, Saraiva, Ligia M, McLean, Kirsty J, Munro, Andrew W, Ferguson, Stuart J, Pickersgill, Richard W, Brown, David G, Warren, Martin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145669/
https://www.ncbi.nlm.nih.gov/pubmed/24865947
http://dx.doi.org/10.1111/mmi.12656