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A New Method To Determine In Vivo Interactomes Reveals Binding of the Legionella pneumophila Effector PieE to Multiple Rab GTPases

Legionella pneumophila, the causative agent of Legionnaires’ disease, uses the Dot/Icm type IV secretion system (T4SS) to translocate more than 300 effectors into host cells, where they subvert host cell signaling. The function and host cell targets of most effectors remain unknown. PieE is a 69-kDa...

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Detalles Bibliográficos
Autores principales: Mousnier, Aurélie, Schroeder, Gunnar N., Stoneham, Charlotte A., So, Ernest C., Garnett, James A., Yu, Lu, Matthews, Steve J., Choudhary, Jyoti S., Hartland, Elizabeth L., Frankel, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145681/
https://www.ncbi.nlm.nih.gov/pubmed/25118235
http://dx.doi.org/10.1128/mBio.01148-14