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Whole-Animal Chemical Screen Identifies Colistin as a New Immunomodulator That Targets Conserved Pathways
The purpose of this study was to take advantage of the nematode Caenorhabditis elegans to perform a whole-animal chemical screen to identify potential immune activators that may confer protection against bacterial infections. We identified 45 marketed drugs, out of 1,120 studied compounds, that are...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Microbiology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145682/ https://www.ncbi.nlm.nih.gov/pubmed/25118236 http://dx.doi.org/10.1128/mBio.01235-14 |