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Reconstructing lineage hierarchies of the distal lung epithelium using single cell RNA-seq

The mammalian lung is a highly branched network, in which the distal regions of the bronchial tree transform during development into a densely packed honeycomb of alveolar air sacs that mediate gas exchange. Although this transformation has been studied by marker expression analysis and fate-mapping...

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Detalles Bibliográficos
Autores principales: Treutlein, Barbara, Brownfield, Doug G., Wu, Angela R., Neff, Norma F., Mantalas, Gary L., Espinoza, F. Hernan, Desai, Tushar J., Krasnow, Mark A., Quake, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145853/
https://www.ncbi.nlm.nih.gov/pubmed/24739965
http://dx.doi.org/10.1038/nature13173