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Reconstructing lineage hierarchies of the distal lung epithelium using single cell RNA-seq
The mammalian lung is a highly branched network, in which the distal regions of the bronchial tree transform during development into a densely packed honeycomb of alveolar air sacs that mediate gas exchange. Although this transformation has been studied by marker expression analysis and fate-mapping...
Autores principales: | Treutlein, Barbara, Brownfield, Doug G., Wu, Angela R., Neff, Norma F., Mantalas, Gary L., Espinoza, F. Hernan, Desai, Tushar J., Krasnow, Mark A., Quake, Stephen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145853/ https://www.ncbi.nlm.nih.gov/pubmed/24739965 http://dx.doi.org/10.1038/nature13173 |
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