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Mechanisms of NOS1AP action on NMDA receptor-nNOS signaling

NMDA receptors (NMDAR) are glutamate-gated calcium channels that play pivotal roles in fundamental aspects of neuronal function. Dysregulated receptor function contributes to many disorders. Recruitment by NMDARs of calcium-dependent enzyme nNOS via PSD95 is seen as a key contributor to neuronal dys...

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Detalles Bibliográficos
Autores principales: Courtney, Michael J., Li, Li-Li, Lai, Yvonne Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145862/
https://www.ncbi.nlm.nih.gov/pubmed/25221472
http://dx.doi.org/10.3389/fncel.2014.00252