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Calpain mediated cisplatin-induced ototoxicity in mice

Ototoxic drug-induced apoptosis of inner ear cells has been shown to be associated with calpain expression. Cisplatin has severe ototoxicity, and can induce cochlear cell apoptosis. This study assumed that cisplatin activated calpain expression in apoptotic cochlear cells. A mouse model of cisplatin...

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Detalles Bibliográficos
Autores principales: Chang, Liang, Wang, Aimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145908/
https://www.ncbi.nlm.nih.gov/pubmed/25206508
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.21.008