A new DNA vaccine fused with the C3d-p28 induces a Th2 immune response against amyloid-beta

To enhance anti-amyloid-beta (Aβ) antibody generation and induce a Th2 immune response, we constructed a new DNA vaccine p(Aβ(3–10))10-C3d-p28.3 encoding ten repeats of Aβ(3–10) and three copies of C3d-p28 as a molecular adjuvant. In this study, we administered this adjuvant cularly to female C57BL/...

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Detalles Bibliográficos
Autores principales: Guo, Wanshu, Sha, Sha, Jiang, Tongzi, Xing, Xiaona, Cao, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Research and Report Article: Neurodegenerative Disease and Neural Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145937/
https://www.ncbi.nlm.nih.gov/pubmed/25206569
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.27.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145937/
https://www.ncbi.nlm.nih.gov/pubmed/25206569
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.27.010

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