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A new DNA vaccine fused with the C3d-p28 induces a Th2 immune response against amyloid-beta
To enhance anti-amyloid-beta (Aβ) antibody generation and induce a Th2 immune response, we constructed a new DNA vaccine p(Aβ(3–10))10-C3d-p28.3 encoding ten repeats of Aβ(3–10) and three copies of C3d-p28 as a molecular adjuvant. In this study, we administered this adjuvant cularly to female C57BL/...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145937/ https://www.ncbi.nlm.nih.gov/pubmed/25206569 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.27.010 |