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Nuclear TAR DNA-binding protein 43: A new target for amyotrophic lateral sclerosis treatment

Abnormal TAR DNA-binding protein 43 (TDP-43) inclusion bodies can be detected in the degenerative neurons of amyotrophic lateral sclerosis. In this study, we induced chronic oxidative stress injury by applying malonate to cultured mouse cortical motor neurons. In the later stages of the malonate ins...

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Detalles Bibliográficos
Autores principales: Zheng, Mei, Shi, Yujie, Fan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145946/
https://www.ncbi.nlm.nih.gov/pubmed/25206650
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.35.003