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Calcium-dependent proteasome activation is required for axonal neurofilament degradation

Even though many studies have identified roles of proteasomes in axonal degeneration, the molecular mechanisms by which axonal injury regulates proteasome activity are still unclear. In the present study, we found evidence indicating that extracellular calcium influx is an upstream regulator of prot...

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Detalles Bibliográficos
Autores principales: Park, Joo Youn, Jang, So Young, Shin, Yoon Kyung, Suh, Duk Joon, Park, Hwan Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146008/
https://www.ncbi.nlm.nih.gov/pubmed/25206662
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.36.005