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Calcium-dependent proteasome activation is required for axonal neurofilament degradation
Even though many studies have identified roles of proteasomes in axonal degeneration, the molecular mechanisms by which axonal injury regulates proteasome activity are still unclear. In the present study, we found evidence indicating that extracellular calcium influx is an upstream regulator of prot...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146008/ https://www.ncbi.nlm.nih.gov/pubmed/25206662 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.36.005 |