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Metabolic alteration of neuroactive steroids and protective effect of progesterone in Alzheimer's disease-like rats

A correlation between metabolic alterations of neuroactive steroids and Alzheimer's disease remains unknown. In the present study, amyloid beta (Aβ) 25–35 (Aβ(25–35)) injected into the bilateral hippocampus CA1 region significantly reduced learning and memory. At the biochemical level, hippocam...

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Detalles Bibliográficos
Autores principales: Liu, Sha, Wu, Honghai, Xue, Gai, Ma, Xin, Wu, Jie, Qin, Yabin, Hou, Yanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146013/
https://www.ncbi.nlm.nih.gov/pubmed/25206601
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.30.002