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Insights into the structural biology of G-protein coupled receptors impacts drug design for central nervous system neurodegenerative processes

In the last few years, there have been important new insights into the structural biology of G-protein coupled receptors. It is now known that allosteric binding sites are involved in the affinity and selectivity of ligands for G-protein coupled receptors, and that signaling by these receptors invol...

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Detalles Bibliográficos
Autores principales: Dalet, Farfán-García Eunice, Guadalupe, Trujillo-Ferrara José, María del Carmen, Castillo-Hernández, Humberto, Guerra-Araiza Christian, Antonio, Soriano-Ursúa Marvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146033/
https://www.ncbi.nlm.nih.gov/pubmed/25206539
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.009