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Insights into the structural biology of G-protein coupled receptors impacts drug design for central nervous system neurodegenerative processes
In the last few years, there have been important new insights into the structural biology of G-protein coupled receptors. It is now known that allosteric binding sites are involved in the affinity and selectivity of ligands for G-protein coupled receptors, and that signaling by these receptors invol...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146033/ https://www.ncbi.nlm.nih.gov/pubmed/25206539 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.009 |