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Autophagy and neurodegenerative disorders

Accumulation of aberrant proteins and inclusion bodies are hallmarks in most neurodegenerative diseases. Consequently, these aggregates within neurons lead to toxic effects, overproduction of reactive oxygen species and oxidative stress. Autophagy is a significant intracellular mechanism that remove...

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Detalles Bibliográficos
Autores principales: Kesidou, Evangelia, Lagoudaki, Roza, Touloumi, Olga, Poulatsidou, Kyriaki-Nefeli, Simeonidou, Constantina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146038/
https://www.ncbi.nlm.nih.gov/pubmed/25206537
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.007