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Protective effect of alpha-synuclein knockdown on methamphetamine-induced neurotoxicity in dopaminergic neurons

The over-expression of α-synuclein is a major factor in the death of dopaminergic neurons in a methamphetamine-induced model of Parkinson's disease. In the present study, α-synuclein knockdown rats were created by injecting α-synuclein-shRNA lentivirus stereotaxically into the right striatum of...

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Detalles Bibliográficos
Autores principales: Tai, Yunchun, Chen, Ling, Huang, Enping, Liu, Chao, Yang, Xingyi, Qiu, Pingming, Wang, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146216/
https://www.ncbi.nlm.nih.gov/pubmed/25206917
http://dx.doi.org/10.4103/1673-5374.133146