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Fusion protein of single-chain variable domain fragments for treatment of myasthenia gravis

Single-chain variable domain fragment (scFv) 637 is an antigen-specific scFv of myasthenia gravis. In this study, scFv and human serum albumin genes were conjugated and the fusion protein was expressed in Pichia pastoris. The affinity of scFv-human serum albumin fusion protein to bind to acetylcholi...

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Detalles Bibliográficos
Autores principales: Li, Fangfang, Meng, Fanping, Jin, Quanxin, Sun, Changyuan, Li, Yingxin, Li, Honghua, Jin, Songzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146252/
https://www.ncbi.nlm.nih.gov/pubmed/25206900
http://dx.doi.org/10.4103/1673-5374.131611