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Adipose-derived mesenchymal stem cell transplantation promotes adult neurogenesis in the brains of Alzheimer's disease mice

In the present study, we transplanted adipose-derived mesenchymal stem cells into the hippocampi of APP/PS1 transgenic Alzheimer's disease model mice. Immunofluorescence staining revealed that the number of newly generated (BrdU(+)) cells in the subgranular zone of the dentate gyrus in the hipp...

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Detalles Bibliográficos
Autores principales: Yan, Yufang, Ma, Tuo, Gong, Kai, Ao, Qiang, Zhang, Xiufang, Gong, Yandao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146257/
https://www.ncbi.nlm.nih.gov/pubmed/25206892
http://dx.doi.org/10.4103/1673-5374.131596