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Nasal mucosal inhalation of amyloid-beta peptide 3–10 defective adenovirus attenuates cytotoxicity induced by beta-amyloid (1–42)
Three-month-old Alzheimer's disease model transgenic mice were immunized with Aβ(1–42) Plp-Adenovirus [Ad]-X-CMV-(Aβ(3–10))(10)-CpG [AdCpG-(Aβ(3–10))(10)] or AdCpG virus fluid via nasal mucosal inhalation, respectively. ELISA analysis of serum showed Aβ(42) antibody titers were significantly in...
Autores principales: | Jiang, Tongzi, Guo, Wanshu, Sha, Sha, Xing, Xiaona, Guo, Rong, Cao, Yunpeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146261/ https://www.ncbi.nlm.nih.gov/pubmed/25206904 http://dx.doi.org/10.4103/1673-5374.131605 |
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