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Chemokine receptor 4 gene silencing blocks neuroblastoma metastasis in vitro

This study investigated the effects of small interfering RNA (siRNA)-mediated silencing of chemokine receptor 4 (CXCR4) on the invasion capacity of human neuroblastoma cell line SH-SY5Y in vitro. Three siRNAs targeting CXCR4 were chemically synthesized and individually transfected into SH-SY5Y cells...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Zhu, Yongjie, Han, Lulu, Lu, Hongting, Hao, Xiwei, Dong, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146301/
https://www.ncbi.nlm.nih.gov/pubmed/25206760
http://dx.doi.org/10.4103/1673-5374.133172