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Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimer's disease

Amyloid-beta peptide is the main component of amyloid plaques, which are found in Alzheimer's disease. The generation and deposition of amyloid-beta is one of the crucial factors for the onset and progression of Alzheimer's disease. Lipid rafts are glycolipid-rich liquid domains of the pla...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Yang, Chun, Liu, Yufeng, Li, Peng, Yang, Huiying, Dai, Jingxing, Qu, Rongmei, Yuan, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146310/
https://www.ncbi.nlm.nih.gov/pubmed/25206748
http://dx.doi.org/10.4103/1673-5374.125335