Dab2 attenuates brain injury in APP/PS1 mice via targeting transforming growth factor-beta/SMAD signaling

Transforming growth factor-beta (TGF-β) type II receptor (TβRII) levels are extremely low in the brain tissue of patients with Alzheimer's disease. This receptor inhibits TGF-β1/SMAD signaling and thereby aggravates amyolid-beta deposition and neuronal injury. Dab2, a specific adapter protein,...

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Detalles Bibliográficos
Autores principales: Song, Lei, Gu, Yue, Jie, Jing, Bai, Xiaoxue, Yang, Ying, Liu, Chaoying, Liu, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Research and Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146324/
https://www.ncbi.nlm.nih.gov/pubmed/25206742
http://dx.doi.org/10.4103/1673-5374.125328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146324/
https://www.ncbi.nlm.nih.gov/pubmed/25206742
http://dx.doi.org/10.4103/1673-5374.125328

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