Charged Residues Distribution Modulates Selectivity of the Open State of Human Isoforms of the Voltage Dependent Anion-Selective Channel

Voltage Dependent Anion-selective Channels (VDACs) are pore-forming proteins located in the outer mitochondrial membrane. They are responsible for the access of ions and energetic metabolites into the inner membrane transport systems. Three VDAC isoforms exist in mammalian, but their specific role i...

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Detalles Bibliográficos
Autores principales: Amodeo, Giuseppe Federico, Scorciapino, Mariano Andrea, Messina, Angela, De Pinto, Vito, Ceccarelli, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146382/
https://www.ncbi.nlm.nih.gov/pubmed/25084457
http://dx.doi.org/10.1371/journal.pone.0103879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146382/
https://www.ncbi.nlm.nih.gov/pubmed/25084457
http://dx.doi.org/10.1371/journal.pone.0103879

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