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Charged Residues Distribution Modulates Selectivity of the Open State of Human Isoforms of the Voltage Dependent Anion-Selective Channel
Voltage Dependent Anion-selective Channels (VDACs) are pore-forming proteins located in the outer mitochondrial membrane. They are responsible for the access of ions and energetic metabolites into the inner membrane transport systems. Three VDAC isoforms exist in mammalian, but their specific role i...
Autores principales: | Amodeo, Giuseppe Federico, Scorciapino, Mariano Andrea, Messina, Angela, De Pinto, Vito, Ceccarelli, Matteo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146382/ https://www.ncbi.nlm.nih.gov/pubmed/25084457 http://dx.doi.org/10.1371/journal.pone.0103879 |
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