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Coordinated repression and activation of two transcriptional programs stabilizes cell fate during myogenesis

Molecular models of cell fate specification typically focus on the activation of specific lineage programs. However, the concurrent repression of unwanted transcriptional networks is also essential to stabilize certain cellular identities, as shown in a number of diverse systems and phyla. Here, we...

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Detalles Bibliográficos
Autores principales: Ciglar, Lucia, Girardot, Charles, Wilczyński, Bartek, Braun, Martina, Furlong, Eileen E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146391/
https://www.ncbi.nlm.nih.gov/pubmed/24961800
http://dx.doi.org/10.1242/dev.101956