Mirk/dyrk1B kinase is upregulated following inhibition of mTOR

The PI3K/PTEN/Akt/mTOR/p70S6K pathway is one of the most frequently deregulated signaling pathways in solid tumors and has a functional role in drug resistance. However, targeting this pathway leads to compensatory activation of several mediators of cell survival. Expression of the reactive oxygen s...

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Detalles Bibliográficos
Autores principales: Deng, Xiaobing, Hu, Jing, Ewton, Daina Z., Friedman, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Manuscript
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146409/
https://www.ncbi.nlm.nih.gov/pubmed/24590896
http://dx.doi.org/10.1093/carcin/bgu058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146409/
https://www.ncbi.nlm.nih.gov/pubmed/24590896
http://dx.doi.org/10.1093/carcin/bgu058

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