Hemagglutinin 222D/G Polymorphism Facilitates Fast Intra-Host Evolution of Pandemic (H1N1) 2009 Influenza A Viruses

The amino acid substitution of aspartic acid to glycine in hemagglutinin (HA) in position 222 (HA-D222G) as well as HA-222D/G polymorphism of pandemic (H1N1) 2009 influenza viruses (A(H1N1)pdm09) were frequently reported in severe influenza in humans and mice. Their impact on viral pathogenicity and...

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Detalles Bibliográficos
Autores principales: Seidel, Nora, Sauerbrei, Andreas, Wutzler, Peter, Schmidtke, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146462/
https://www.ncbi.nlm.nih.gov/pubmed/25162520
http://dx.doi.org/10.1371/journal.pone.0104233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146462/
https://www.ncbi.nlm.nih.gov/pubmed/25162520
http://dx.doi.org/10.1371/journal.pone.0104233

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