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In Silico Determination of the Effect of Multi-Target Drugs on Calcium Dynamics Signaling Network Underlying Sea Urchin Spermatozoa Motility

The motility of spermatozoa of both Lytechinus pictus and Strongylocentrotus purpuratus sea urchin species is modulated by the egg-derived decapeptide speract via an oscillatory [Ca(2+)]-dependent signaling pathway. Comprehension of this pathway is hence directly related to the understanding of regu...

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Detalles Bibliográficos
Autores principales: Espinal-Enríquez, Jesús, Darszon, Alberto, Guerrero, Adán, Martínez-Mekler, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146467/
https://www.ncbi.nlm.nih.gov/pubmed/25162222
http://dx.doi.org/10.1371/journal.pone.0104451