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Early Biodistribution and Persistence of a Protective Live Attenuated SIV Vaccine Elicits Localised Innate Responses in Multiple Lymphoid Tissues

Vaccination of Mauritian cynomolgus macaques with the attenuated nef-truncated C8 variant of SIVmac251/32H (SIVmacC8) induces early, potent protection against pathogenic, heterologous challenge before the maturation of cognate immunity. To identify processes that contribute to early protection in th...

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Detalles Bibliográficos
Autores principales: Ferguson, Deborah, Mattiuzzo, Giada, Ham, Claire, Stebbings, Richard, Li, Bo, Rose, Nicola J., Mee, Edward T., Smith, Deborah, Page, Mark, Cranage, Martin P., Almond, Neil, Towers, Greg J., Berry, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146474/
https://www.ncbi.nlm.nih.gov/pubmed/25162725
http://dx.doi.org/10.1371/journal.pone.0104390