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Early Biodistribution and Persistence of a Protective Live Attenuated SIV Vaccine Elicits Localised Innate Responses in Multiple Lymphoid Tissues
Vaccination of Mauritian cynomolgus macaques with the attenuated nef-truncated C8 variant of SIVmac251/32H (SIVmacC8) induces early, potent protection against pathogenic, heterologous challenge before the maturation of cognate immunity. To identify processes that contribute to early protection in th...
Autores principales: | Ferguson, Deborah, Mattiuzzo, Giada, Ham, Claire, Stebbings, Richard, Li, Bo, Rose, Nicola J., Mee, Edward T., Smith, Deborah, Page, Mark, Cranage, Martin P., Almond, Neil, Towers, Greg J., Berry, Neil J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146474/ https://www.ncbi.nlm.nih.gov/pubmed/25162725 http://dx.doi.org/10.1371/journal.pone.0104390 |
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