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The splicing activator DAZAP1 integrates splicing control into MEK/Erk regulated cell proliferation and migration

Alternative splicing of pre-mRNA is a critical stage of gene regulation in response to environmental stimuli. Here we show that DAZAP1, an RNA binding protein involved in mammalian development and spermatogenesis, promotes inclusion of weak exons through specific recognition of diverse cis-elements....

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Detalles Bibliográficos
Autores principales: Choudhury, Rajarshi, Roy, Sreerupa Ghose, Tsai, Yihsuan S., Tripathy, Ashutosh, Graves, Lee M., Wang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146490/
https://www.ncbi.nlm.nih.gov/pubmed/24452013
http://dx.doi.org/10.1038/ncomms4078