The Jak2 Small Molecule Inhibitor, G6, Reduces the Tumorigenic Potential of T98G Glioblastoma Cells In Vitro and In Vivo

Glioblastoma multiforme (GBM) is the most common and the most aggressive form of primary brain tumor. Jak2 is a non-receptor tyrosine kinase that is involved in proliferative signaling through its association with various cell surface receptors. Hyperactive Jak2 signaling has been implicated in nume...

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Detalles Bibliográficos
Autores principales: Baskin, Rebekah, Park, Sung O., Keserű, György M., Bisht, Kirpal S., Wamsley, Heather L., Sayeski, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146502/
https://www.ncbi.nlm.nih.gov/pubmed/25162558
http://dx.doi.org/10.1371/journal.pone.0105568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146502/
https://www.ncbi.nlm.nih.gov/pubmed/25162558
http://dx.doi.org/10.1371/journal.pone.0105568

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