G Protein Beta 5 Is Targeted to D2-Dopamine Receptor-Containing Biochemical Compartments and Blocks Dopamine-Dependent Receptor Internalization

G beta 5 (Gbeta5, Gβ5) is a unique G protein β subunit that is thought to be expressed as an obligate heterodimer with R7 regulator of G protein signaling (RGS) proteins instead of with G gamma (Gγ) subunits. We found that D2-dopamine receptor (D2R) coexpression enhances the expression of Gβ5, but n...

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Detalles Bibliográficos
Autores principales: Octeau, J. Christopher, Schrader, Joseph M., Masuho, Ikuo, Sharma, Meenakshi, Aiudi, Christopher, Chen, Ching-Kang, Kovoor, Abraham, Celver, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146516/
https://www.ncbi.nlm.nih.gov/pubmed/25162404
http://dx.doi.org/10.1371/journal.pone.0105791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146516/
https://www.ncbi.nlm.nih.gov/pubmed/25162404
http://dx.doi.org/10.1371/journal.pone.0105791

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