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G Protein Beta 5 Is Targeted to D2-Dopamine Receptor-Containing Biochemical Compartments and Blocks Dopamine-Dependent Receptor Internalization
G beta 5 (Gbeta5, Gβ5) is a unique G protein β subunit that is thought to be expressed as an obligate heterodimer with R7 regulator of G protein signaling (RGS) proteins instead of with G gamma (Gγ) subunits. We found that D2-dopamine receptor (D2R) coexpression enhances the expression of Gβ5, but n...
Autores principales: | Octeau, J. Christopher, Schrader, Joseph M., Masuho, Ikuo, Sharma, Meenakshi, Aiudi, Christopher, Chen, Ching-Kang, Kovoor, Abraham, Celver, Jeremy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146516/ https://www.ncbi.nlm.nih.gov/pubmed/25162404 http://dx.doi.org/10.1371/journal.pone.0105791 |
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