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Upregulation of Leukemia Inhibitory Factor (LIF) during the Early Stage of Optic Nerve Regeneration in Zebrafish

Fish retinal ganglion cells (RGCs) can regenerate their axons after optic nerve injury, whereas mammalian RGCs normally fail to do so. Interleukin 6 (IL-6)-type cytokines are involved in cell differentiation, proliferation, survival, and axon regrowth; thus, they may play a role in the regeneration...

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Detalles Bibliográficos
Autores principales: Ogai, Kazuhiro, Kuwana, Ayaka, Hisano, Suguru, Nagashima, Mikiko, Koriyama, Yoshiki, Sugitani, Kayo, Mawatari, Kazuhiro, Nakashima, Hiroshi, Kato, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146584/
https://www.ncbi.nlm.nih.gov/pubmed/25162623
http://dx.doi.org/10.1371/journal.pone.0106010