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Embryonic GABA(B) Receptor Blockade Alters Cell Migration, Adult Hypothalamic Structure, and Anxiety- and Depression-Like Behaviors Sex Specifically in Mice

Neurons of the paraventricular nucleus of the hypothalamus (PVN) regulate the hypothalamic- pituitary-adrenal (HPA) axis and the autonomic nervous system. Females lacking functional GABA(B) receptors because of a genetic disruption of the R1 subunit have altered cellular characteristics in and aroun...

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Detalles Bibliográficos
Autores principales: Stratton, Matthew S., Staros, Michelle, Budefeld, Tomaz, Searcy, Brian T., Nash, Connor, Eitel, Chad, Carbone, David, Handa, Robert J., Majdic, Gregor, Tobet, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146593/
https://www.ncbi.nlm.nih.gov/pubmed/25162235
http://dx.doi.org/10.1371/journal.pone.0106015