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Embryonic GABA(B) Receptor Blockade Alters Cell Migration, Adult Hypothalamic Structure, and Anxiety- and Depression-Like Behaviors Sex Specifically in Mice
Neurons of the paraventricular nucleus of the hypothalamus (PVN) regulate the hypothalamic- pituitary-adrenal (HPA) axis and the autonomic nervous system. Females lacking functional GABA(B) receptors because of a genetic disruption of the R1 subunit have altered cellular characteristics in and aroun...
Autores principales: | Stratton, Matthew S., Staros, Michelle, Budefeld, Tomaz, Searcy, Brian T., Nash, Connor, Eitel, Chad, Carbone, David, Handa, Robert J., Majdic, Gregor, Tobet, Stuart A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146593/ https://www.ncbi.nlm.nih.gov/pubmed/25162235 http://dx.doi.org/10.1371/journal.pone.0106015 |
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