A Critical Role for the mTORC2 Pathway in Lung Fibrosis

A characteristic of dysregulated wound healing in IPF is fibroblastic-mediated damage to lung epithelial cells within fibroblastic foci. In these foci, TGF-β and other growth factors activate fibroblasts that secrete growth factors and matrix regulatory proteins, which activate a fibrotic cascade. O...

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Detalles Bibliográficos
Autores principales: Chang, Wenteh, Wei, Ke, Ho, Lawrence, Berry, Gerald J., Jacobs, Susan S., Chang, Cheryl H., Rosen, Glenn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146613/
https://www.ncbi.nlm.nih.gov/pubmed/25162417
http://dx.doi.org/10.1371/journal.pone.0106155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146613/
https://www.ncbi.nlm.nih.gov/pubmed/25162417
http://dx.doi.org/10.1371/journal.pone.0106155

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