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Scopoletin from Cirsium setidens Increases Melanin Synthesis via CREB Phosphorylation in B16F10 Cells

In this study, we isolated scopoletin from Cirsium setidens Nakai (Compositae) and tested its effects on melanogenesis. Scopoletin was not toxic to cells at concentrations less than 50 µM and increased melanin synthesis in a dose-dependent manner. As melanin synthesis increased, scopoletin stimulate...

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Detalles Bibliográficos
Autores principales: Ahn, Mi-Ja, Hur, Sun-Jung, Kim, Eun-Hyun, Lee, Seung Hoon, Shin, Jun Seob, Kim, Myo-Kyoung, Uchizono, James A., Whang, Wan-Kyunn, Kim, Dong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146632/
https://www.ncbi.nlm.nih.gov/pubmed/25177162
http://dx.doi.org/10.4196/kjpp.2014.18.4.307