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Scopoletin from Cirsium setidens Increases Melanin Synthesis via CREB Phosphorylation in B16F10 Cells
In this study, we isolated scopoletin from Cirsium setidens Nakai (Compositae) and tested its effects on melanogenesis. Scopoletin was not toxic to cells at concentrations less than 50 µM and increased melanin synthesis in a dose-dependent manner. As melanin synthesis increased, scopoletin stimulate...
Autores principales: | Ahn, Mi-Ja, Hur, Sun-Jung, Kim, Eun-Hyun, Lee, Seung Hoon, Shin, Jun Seob, Kim, Myo-Kyoung, Uchizono, James A., Whang, Wan-Kyunn, Kim, Dong-Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146632/ https://www.ncbi.nlm.nih.gov/pubmed/25177162 http://dx.doi.org/10.4196/kjpp.2014.18.4.307 |
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