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Exendin-4 Improves Nonalcoholic Fatty Liver Disease by Regulating Glucose Transporter 4 Expression in ob/ob Mice

Exendin-4 (Ex-4), a glucagon-like peptide-1 receptor (GLP-1R) agonist, has been known to reverse hepatic steatosis in ob/ob mice. Although many studies have evaluated molecular targets of Ex-4, its mechanism of action on hepatic steatosis and fibrosis has not fully been determined. In the liver, glu...

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Detalles Bibliográficos
Autores principales: Kim, Seok, Jung, Jaehoon, Kim, Hwajin, Heo, Rok Won, Yi, Chin-ok, Lee, Jung Eun, Jeon, Byeong Tak, Kim, Won-Ho, Hahm, Jong Ryeal, Roh, Gu Seob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146636/
https://www.ncbi.nlm.nih.gov/pubmed/25177166
http://dx.doi.org/10.4196/kjpp.2014.18.4.333