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Effects of Lubiprostone on Pacemaker Activity of Interstitial Cells of Cajal from the Mouse Colon

Lubiprostone is a chloride (Cl(-)) channel activator derived from prostaglandin E(1) and used for managing constipation. In addition, lubiprostone affects the activity of gastrointestinal smooth muscles. Interstitial cells of Cajal (ICCs) are pacemaker cells that generate slow-wave activity in smoot...

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Detalles Bibliográficos
Autores principales: Jiao, Han-Yi, Kim, Dong Hyun, Ki, Jung Suk, Ryu, Kwon Ho, Choi, Seok, Jun, Jae Yeoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146637/
https://www.ncbi.nlm.nih.gov/pubmed/25177167
http://dx.doi.org/10.4196/kjpp.2014.18.4.341