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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

We conducted a meta analysis of Parkinson’s disease genome-wide association studies using a common set of 7,893,274 variants across 13,708 cases and 95,282 controls. Twenty-six loci were identified as genome-wide significant; these and six additional previously reported loci were then tested in an i...

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Detalles Bibliográficos
Autores principales: Nalls, Mike A, Pankratz, Nathan, Lill, Christina M., Do, Chuong B, Hernandez, Dena G., Saad, Mohamad, DeStefano, Anita L., Kara, Eleanna, Bras, Jose, Sharma, Manu, Schulte, Claudia, Keller, Margaux F., Arepalli, Sampath, Letson, Christopher, Edsall, Connor, Stefansson, Hreinn, Liu, Xinmin, Pliner, Hannah, Lee, Joseph H., Cheng, Rong, Ikram, M. Arfan, Ioannidis, John P.A., Hadjigeorgiou, Georgios M., Bis, Joshua C., Martinez, Maria, Perlmutter, Joel S., Goate, Alison, Marder, Karen, Fiske, Brian, Sutherland, Margaret, Xiromerisiou, Georgia, Myers, Richard H., Clark, Lorraine N, Stefansson, Kari, Hardy, John A., Heutink, Peter, Chen, Honglei, Wood, Nicholas W., Houlden, Henry, Payami, Haydeh, Brice, Alexis, Scott, William K, Gasser, Thomas, Bertram, Lars, Eriksson, Nicholas, Foroud, Tatiana, Singleton, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146673/
https://www.ncbi.nlm.nih.gov/pubmed/25064009
http://dx.doi.org/10.1038/ng.3043