Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss

Head and neck squamous cell carcinoma (HNSCC) is characterized by aggressive behavior with a propensity for metastasis and recurrence. Here we report a comprehensive analysis of the molecular and clinical features of HNSCC that govern patient survival. We find that TP53 mutation is frequently accomp...

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Detalles Bibliográficos
Autores principales: Gross, Andrew M, Orosco, Ryan K, Shen, John P, Egloff, Ann Marie, Carter, Hannah, Hofree, Matan, Choueiri, Michel, Coffey, Charles S, Lippman, Scott M, Hayes, D. Neil, Cohen, Ezra E, Grandis, Jennifer R, Nguyen, Quyen T, Ideker, Trey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146706/
https://www.ncbi.nlm.nih.gov/pubmed/25086664
http://dx.doi.org/10.1038/ng.3051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146706/
https://www.ncbi.nlm.nih.gov/pubmed/25086664
http://dx.doi.org/10.1038/ng.3051

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