N-glycosylation site occupancy in human prostaglandin H synthases expressed in Pichia pastoris

Prostaglandin H synthases (PGHSs) are N-glycosylated membrane proteins that catalyse the committed step in prostaglandin synthesis. Unlike PGHS-2, the production of recombinant PGHS-1 in non-mammalian expression systems is complicated. The majority of the heterologous enzyme is inactive due to misfo...

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Detalles Bibliográficos
Autores principales: Kukk, Kaia, Kasvandik, Sergo, Samel, Nigulas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147080/
https://www.ncbi.nlm.nih.gov/pubmed/25170432
http://dx.doi.org/10.1186/2193-1801-3-436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147080/
https://www.ncbi.nlm.nih.gov/pubmed/25170432
http://dx.doi.org/10.1186/2193-1801-3-436

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