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N-glycosylation site occupancy in human prostaglandin H synthases expressed in Pichia pastoris

Prostaglandin H synthases (PGHSs) are N-glycosylated membrane proteins that catalyse the committed step in prostaglandin synthesis. Unlike PGHS-2, the production of recombinant PGHS-1 in non-mammalian expression systems is complicated. The majority of the heterologous enzyme is inactive due to misfo...

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Detalles Bibliográficos
Autores principales:	Kukk, Kaia, Kasvandik, Sergo, Samel, Nigulas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147080/ https://www.ncbi.nlm.nih.gov/pubmed/25170432 http://dx.doi.org/10.1186/2193-1801-3-436

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