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An Investigation on Mitochondrial DNA Deletions and Telomere Shortening during Multiple Passages of Adult Stem Cells
BACKGROUND: Limited resources for adult stem cells necessitate their in vitro culture prior to clinical use. Investigating mitochondrial DNA (mtDNA) and telomere shortening has proved to be important indications of stem cell validity. This study was designed to investigate these indicators in multip...
Autores principales: | Fesahat, Farzaneh, Sheikhha, Mohammad Hasan, Rasti, Azam, Nodoshan, Fatemeh Sadeghian, Zare-Zardini, Hadi, Navabazam, Ali Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Avicenna Research Institute
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147102/ https://www.ncbi.nlm.nih.gov/pubmed/25215179 |
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