Cargando…
Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage
BACKGROUND: The toxicity of heme breakdown products may contribute to the pathogenesis of intracerebral hemorrhage (ICH). Heme catabolism is catalyzed by the heme oxygenase enzymes. We have previously reported that heme oxygenase-2 (HO-2), the constitutive isoform, protects neurons from hemin in vit...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147166/ https://www.ncbi.nlm.nih.gov/pubmed/25149897 http://dx.doi.org/10.1186/1756-0500-7-561 |