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Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage

BACKGROUND: The toxicity of heme breakdown products may contribute to the pathogenesis of intracerebral hemorrhage (ICH). Heme catabolism is catalyzed by the heme oxygenase enzymes. We have previously reported that heme oxygenase-2 (HO-2), the constitutive isoform, protects neurons from hemin in vit...

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Detalles Bibliográficos
Autores principales:	Chen-Roetling, Jing, Cai, Ying, Regan, Raymond F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147166/ https://www.ncbi.nlm.nih.gov/pubmed/25149897 http://dx.doi.org/10.1186/1756-0500-7-561

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