Insulin Preconditioning Elevates p-Akt and Cardiac Contractility after Reperfusion in the Isolated Ischemic Rat Heart

Insulin induces cardioprotection partly via an antiapoptotic effect. However, the optimal timing of insulin administration for the best quality cardioprotection remains unclear. We tested the hypothesis that insulin administered prior to ischemia provides better cardioprotection than insulin adminis...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Tamaki, Sato, Hiroaki, Oguchi, Takeshi, Fukushima, Hisashi, Carvalho, George, Lattermann, Ralph, Matsukawa, Takashi, Schricker, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147204/
https://www.ncbi.nlm.nih.gov/pubmed/25197648
http://dx.doi.org/10.1155/2014/536510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147204/
https://www.ncbi.nlm.nih.gov/pubmed/25197648
http://dx.doi.org/10.1155/2014/536510

Ejemplares similares